The DBEI distinctively brings together expertise in biostatistics, epidemiology and informatics, to advance population-health science.
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Penn Medicine researchers will help lead the development of an algorithm to flag patients at risk of rare disease thanks to a $4.7 million NIH grant. This 4-year U01 will involve 10 national health systems (with a total of 27 million patients) for developing federated learning and transfer learning algorithms using real-world data for early detection of rare diseases.
The efforts to develop this prediction method, called “PANDA: Predictive Analytics via Networked Distributed Algorithms for multi-system diseases,” will be led by principal investigators from the DBEI Drs. Yong Chen, Professor of Biostatistics, and Peter A. Merkel, Chief of Rheumatology and a Professor of Medicine and Epidemiology, as well as Jiang Bian, Chief Data Scientist of the University of Florida Health System and a Professor in the Health Outcomes & Biomedical Informatics at the University of Florida College of Medicine.
First study author, Joel M. Gelfand, MD, MSCE, and the investigators discovered that apremilast (brand name Otezla), which has helped psoriasis patients achieve clearer skin and ease the symptoms of their psoriatic arthritis, could also help people with psoriasis shed unhealthy body fat and therefore improve cardiovascular health, a well-known vulnerability for those with psoriasis.
Read the article in JAMA Dermatology.
Joe Biden says the pandemic is over. Experts said the definition of a pandemic depends on how society reacts. But is it?
To understand health and disease today, we need new thinking and novel science —the kind we create when multiple disciplines work together from the ground up. That is why this department has put forward a bold vision in population-health science: a single academic home for biostatistics, epidemiology and informatics. LEARN MORE ABOUT US